LENWOOD Two men suffered major injuries after the semi-truck they were riding in caught fire following a pre-dawn Thursday morning crash on Interstate 15, Barstow California Highway Patrol Officer Don Spiker said.

At 3:30 A.M., Barstow CHP received a report of the single-vehicle accident.

The semi was traveling southbound on the I-15, south of Wild Wash Road, when it veered to the right for reasons still unknown, collided into a guardrail and rolled down a roadside embankment, Spiker said.

The cab caught fire and the trailer suffered damage from smoldering. The trailer was not engulfed in flames, Barstow CHP Officer Adam Croxton confirmed.

Both men in the semi were airlifted to Arrowhead Regional Medical Center in Colton for treatment of major injuries.

The Wild Wash Road offramp was closed while clean-up crews worked to recover the semi and surrounding debris, but Croxton said no lanes on the I-15 were blocked.

It was originally believed hazardous material crews had be called in to handle potential leakage from the semi, but nothing spilled out, Croxton later said.

CHP, Desert Ambulance, the Barstow Fire Protection District and American Tow responded to the scene, Spiker confirmed.

CHP is investigating the incident.

Shea Johnson may be reached at (760) 256-4126 or at SJohnson@DesertDispatch.com.